When I was using a wireless webcam I would occasionally get very frustrating and misleading errors in IS. I finally learned to sort the ImageSalsa directory in Windows Explorer by date, most recent first. I would then delete all of the obviously recent data files and IS would happily run once again. I recall that a corrupt data file will render IS inoperative. Since I switched to a wired webcam last fall I haven't had a single such problem. Don't delete any initialization files, just one, two, or possibly three *.csv, *.tmp, or *.bin files.
Try it. You don't have much to lose at this point.