No magic bullets, but the most common cause of slow down on MS based machines in memory leaks, that is programs and processes that do not release memory when they conclude, that memory remains locked out to other processes and programs and eventually the system is using a large amount of swap file (artificial memory on a disk, where non active memory is transfered till it is needed in ram) the time for transfer from ram to disk is the cause of slowness. Look for evidence of lots of disk activity and look at task managers performance and stats tabs. Access task manager by right clicking task bar and selecting task manager.