As noted, it's possible to do 2 complete stations in the same location on 2 different ISS IDs. I did an installation on a local ranch with 5 stations and 3 repeaters, all the consoles in the same room.
In addition, if one of the consoles is a VP2, the second station can be received by it as a temperature/humidity station. I'm doing that here. The main VP2 station up at the house received Station 2 down in the woods as temp/hum while the Vue console down there receives it as a full station.